Apolipoprotein D Antibody Staining Protocol for Immunohistochemistry

Description: Apolipoprotein D is a glycoprotein involved in the human plasma lipid transport system. It is mainly associated with high density lipoprotein particles and forms disulphide-linked heterodimers with other apolipoproteins. The function of apolipoprotein D in the metabolism of plasma lipoproteins is unclear but the observation that this protein forms complexes with lecithin: cholesterol acyltransferase has led to the suggestion that apolipoprotein D may be involved in cholesterol esterification and transport of substrates and products of the reaction. Apolipoprotein D is expressed in a range of normal tissues including axillary apocrine glands, adrenal cortex and corpus luteum. Peripheral nerves, pituitary, testis, cerebellum and renal tubes are also positive.