alpha-Tubulin IHC Antibody, Ready to Use

 

alpha-Tubulin IHC Antibody

 

Ready To Use

 

Catalog Number Size Price Availability
IW-MA1107 9 ml $258 Yes

Description

 

alpha-tubulin (b-alpha-1) mRNA is expressed only in brain with a molecular weight of about 55,000. The 3-prime UTR of b-alpha-1 is more than 80% homologous to the UTR of the rat brain alpha-tubulin gene, IL-alpha-T1. B-alpha-1 encodes a predicted 451-amino acid protein that is 100% identical to the rat homolog and differs by only 2 and 3 amino acids from the pig and chicken homologs, respectively.

 

Catalog Number

 

IW-MA1107

Quantity

 

9 ml

Host

 

Mouse

 

Clone

 

Tub-1

 

Isotype

 

Mouse IgG1

 

Immunogen

 

Microtubules from chicken embryo brain.

Purity

 

Purified by the goat anti-mouse IgG affinity chromatography.

 

Conjugate

 

Unconjugated

 

Species Reactivity

 

Human, rat. Not tested in other species.

Positive Control

 

Brain

Cellular Localization

 

Cytoplasmic

 

Form

 

Ready to use solution. No further dilution needed. Serum blocking step should be omitted.

 

Storage

 

Store at 2-8 °C. Do not freeze.

 

Applications

 

IHC-P: Heat induced epitope retrieval is required on formalin fixed paraffin sections.

IHC-Fr: Not tested.

ICC: Not tested.

 

Limitations

 

This product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.

 

Precautions

 

Users should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.

 

References

 

1. Cowan, N. J.; Dobner, P. R.; Fuchs, E. V.; Cleveland, D. W. : Expression of human alpha-tubulin genes: interspecies conservation of 3-prime untranslated regions. Molec. Cell. Biol. 3: 1738-1745, 1983.

2. Hall, J. L.; Cowan, N. J. : Structural features and restricted expression of a human alpha-tubulin gene. Nucleic Acids Res. 13: 207-223, 1985.

 

Images

 

Immunohistochemistry staining of formalin fixed paraffin embedded human mammary cancer using alpha-Tubulin antibody showing cytoplasmic staining.

 

 

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