ABC of Safety in the Biological Sciences - Haematoxylin

 

ABC of Safety in the Biological Sciences

 


 

HAEMATOXYLIN Colour Index N. 75290 (C16H14O6.3H20)

SYNONYMS
Natural black 1; hematoxiline, hydroxybrazilin, hydroxybrasilinin.
GENERAL PRECAUTIONS
Avoid skin and eye contact.
Avoid inhalation of the dust.
Keep away from heat or naked flames.
Keep in a tightly sealed container in the dark.
Wash hands thoroughly after handling.
CHARACTERISTICS
White to yellow to light brown crystals or crystalline powder. Natural dye.
HEALTH HAZARD DATA
This substance is combustible and should not be handled close to heat or a naked flame. The toxicity of haematoxylin has not been quantified but because of its chemical structure it is deemed to be a mild irritant and mildly toxic.
TREATMENTS
Skin ­ immediately wash the affected area with soap or mild detergent and water until all evidence of the dye has been removed (approximately 15 minutes).
Eyes ­ immediately wash the affected eye with large amounts of water until all evidence of the dye has been removed (approximately 15 minutes). If irritation persists seek medical attention.
Inhalation ­ remove from the area of exposure to fresh air. Keep warm and allow to rest. If irritation persists seek medical attention.
Ingestion ­ wash out the mouth with water and give two to four water to drink. Induce vomiting by touching a finger to the back of the throat. If discomfort persists seek medical advice.
INCOMPATIBILITY
Combustible substance ­ keep away from heat or naked flames. Heating produces carbon dioxide. Oxidises on exposure to light. Can react vigorously with oxidising agents and alkalies.
STORAGE
Store in the dark in a cool, dry atmosphere away from heat, oxidising agents and alkalies.
HANDLING
Never handle close to heat or a naked flame. Wear protective clothing. A long sleeved laboratory coat or gown, rubber gloves and safety goggles as a minimum standard.
DISPOSAL
WEAR: Rubber gloves, face shield and laboratory coat. Have an all purpose canister respirator available.
SPILLS: A gas leak - keep the concentration of the gas below the explosive mixture range by forced ventilation. Remove the tank to an open area and allow dissipation to the atmosphere. Attempt to cap the valve outlet and return the tank to the supplier.
A liquid - absorb on paper. Evaporate in an iron pan in a flame proof fume hood then burn the paper. A solid - sweep on to paper and place in an iron pan in a fume hood. Burn the paper and compound.
PACKAGE LOTS: A gas - pipe the gas into an incinerator or lower into a pit and allow to burn.
A liquid - atomise into an incinerator. Combustion may be improved by mixing with a more flammable solvent.
A solid - make up packages in paper or other flammable material. Burn in the incinerator. Or the solid may be dissolved in a flammable solvent and sprayed into a fire chamber.
ENVIRONMENT:

 


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