ABC of Safety in the Biological Sciences - Hydroxyquinoline

 

ABC of Safety in the Biological Sciences

 


 

8­HYDROXYQUINOLINE (HOC6H3N:N:CHCH:CH)

SYNONYMS
Oxine, 8­quinoloinol.
GENERAL PRECAUTIONS
Avoid skin and eye contact.
Avoid inhalation of the powder.
Keep away from heat.
Wash hands thoroughly after handling.
CHARACTERISTICS
White or cream coloured crystals, crystalline powder or flakes.
HEALTH HAZARD DATA
This substance is a skin and eye irritant with relatively low toxicity, but if inhaled or ingested in large amounts it can be harmful.
TREATMENTS
Skin ­ immediately wash the affected area with soap or mild detergent and large amounts of water until all evidence of the chemical has been removed (approximately 15 minutes). If irritation persists seek medical attention.
Eyes ­ immediately wash the affected eye with large amounts of water until all evidence of the chemical has been removed (approximately 15 minutes). If irritation persists seek medical attention.
Inhalation ­ remove from the area of exposure to fresh air. If breathing has ceased apply artificial respiration. Keep warm and allow to rest. In severe cases seek medical attention.
Ingestion ­ wash out the mouth with water and give water to drink. Seek immediate medical advice.
INCOMPATIBILITY
Heating produces highly toxic fumes of nitrogen compounds.
STORAGE
Store in a cool, dry atmosphere away from heat.
HANDLING
Wear protective clothing to avoid skin or eye contact, or inhalation. A long sleeved laboratory coat or gown, rubber gloves, safety goggles and a face mask as a minimum standard.
DISPOSAL
WEAR:
Butyl rubber gloves, laboratory coat and self contained breathing apparatus.
SPILLS:
On skin and clothing: wash skin with strong soap solution immediately. Rinse thoroughly. Contaminated clothing should be removed, dried and washed with strong soap solution or destroyed. It may be necessary to destroy shoes by burning.
Small spills: absorb liquid on paper towels. Brush solids on to paper. Place in an iron pan and allow evaporation in a fume hood. Add crumpled paper and burn. Wash spill site with a strong soap solution.
Large spills: cover with sand and soda ash mixture (90/10). Mix and shovel into a cardboard box. Pack with a large excess of crumpled paper. Burn in an open pit or incinerator equipped with an afterburner and scrubber.
PACKAGE LOTS: Either
1 Pour or sift on to a thick layer of sand and soda ash mixture (90/10). Mix, and shovel into a heavy paper box with much paper packaging. Burn in an incinerator. The fire may be augmented with scrap wood. Stay on the upwind side.
OR
2 Dissolve in a flammable solvent and spray into the firebox of an incinerator equipped with an afterburner and scrubber.
ENVIRONMENT:

 


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