Abcam Ad

Author Topic: activated macrophage  (Read 7298 times)

0 Members and 1 Guest are viewing this topic.

Offline erised

  • Newbie
  • *
  • Posts: 2
activated macrophage
« on: October 03, 2005, 08:33:26 AM »
How to discriminate between activated macrophage and resident macrophage in the liver of mice?

I saw the data sheet of F4/80 Ab said its expression will be downregulated in activated macrophage.

is there any other Ab more specific for the activated macrophage

activated macrophage
« on: October 03, 2005, 08:33:26 AM »

Offline richard03

  • Administrator
  • GoldMember
  • *****
  • Posts: 1212
activated macrophage
« Reply #1 on: October 03, 2005, 01:10:31 PM »
CD68 is an activated macrophage marker.

http://www.jleukbio.org/cgi/content/abstract/74/6/1015

Richard

Offline ImmunoNYC

  • Global Moderator
  • GoldMember
  • *****
  • Posts: 684
Re: activated macrophage
« Reply #2 on: October 04, 2005, 12:27:39 AM »
I have used F4/80 to stain tumor macrophages with good success so I wonder does this mean that these tumor infiltrating macrophages are not activated and instead just leading to a chronic inflammatory state? Thoughts anyone?

Quote from: "erised"
How to discriminate between activated macrophage and resident macrophage in the liver of mice?

I saw the data sheet of F4/80 Ab said its expression will be downregulated in activated macrophage.

is there any other Ab more specific for the activated macrophage

Re: activated macrophage
« Reply #2 on: October 04, 2005, 12:27:39 AM »