The RiboMinus for RNA-sequencing kits are available in two configurations: a universal kit for eukaryotes and a more specialised kit for plants. They are used for the enrichment of RNA for whole transcriptome analysis for ribonucleic acid sequencing or RNA-Sequencing applications. The kit enables the depletion of large ribosomal RNA, the most abundant RNA in the transcriptome, by using oligonucleotide probes containing locking nucleic acids and magnetic bead separation technology. The ability to deplete the ribosomal RNA is significant because the abundant RNAs often mask the messenger RNAs that play an influential role in gene expression, which may affect the detection of novel RNA transcripts within a cell. For example, scientists may use the RiboMinus kit to discover low abundance RNA sequences associated with human disease, as well as in agricultural systems that help determine the factors involved in drought and pest resistance.