Author Topic: Mass spec - receptor variants in tumors  (Read 3186 times)

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Offline sutree

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Mass spec - receptor variants in tumors
« on: September 22, 2010, 12:03:22 AM »
Hello all, I have a prelim coming up where I need to present on methods out of my jurisdiction.

 I would like to take samples of primary tumor and seek out the different variants of two well-characterized receptors that are found in them.

Can I take a tissue lysate, purify for my protein of interest and run a mass spec for this?  Will this tell me the different variations that are present in the tumor?

Any advice or direction is appreciated, cheers.

Mass spec - receptor variants in tumors
« on: September 22, 2010, 12:03:22 AM »