Abcam Ad

Author Topic: Markers for differentiation in Uterus Lesion  (Read 6842 times)

0 Members and 1 Guest are viewing this topic.

Offline msafron

  • Newbie
  • *
  • Posts: 1
Markers for differentiation in Uterus Lesion
« on: November 12, 2004, 01:42:58 PM »
I am looking for the proper antibodies to differenciate between Leiomyoma, histocytic sarcoma, and stromal cell sarcoma of mouse uterus.

Markers for differentiation in Uterus Lesion
« on: November 12, 2004, 01:42:58 PM »

Offline JLI

  • SuperTech
  • ****
  • Posts: 42
Markers for differentiation in Uterus Lesion
« Reply #1 on: November 24, 2004, 04:39:43 PM »
I donīt know much about mice. In humans you could use:

CD68 - Positive in histiocytic sarcoma
h-caldesmon -positive in most leiomyomas, rarely (never??) in  stromal sarcoma
CD44V3 - Positive in most leiomyomas, rarely in stromal sarcoma
CD10 - Positive in most stromal sarcomas, almost never in leiomyomas.

I think the "h" in h-caldesmon stands for human. Maybe there is a similar antibody available for mice.

Jan

Markers for differentiation in Uterus Lesion
« Reply #1 on: November 24, 2004, 04:39:43 PM »