Caspase-9 Antibody Staining Protocol for Immunohistochemistry

Description: Caspase-9 is a member of the caspase family of cysteine proteases that have been implicated in apoptosis and cytokine processing. Caspases have been shown to be activated during normal human keratinocyte differentiation and this activation is required for thecnormal loss of the nucleus. In the presence of ATP, apoptotic stimuli induce proteolytic processing and activation of downstream caspases such as caspase-3, 6 and 7 initiating the caspase cascade. Caspase-9 is essential for apoptosis during the normal development of the central nervous system.