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CRP IHC Antibody
Ready To Use
| Catalog Number | Size | Price | Availability |
| IW-PA1028 | 9 ml | $258 | Yes |
Description
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C Reactive Protein (CRP)
is a major acute phase reactant synthesized primarily in the
liver hepatocytes. It is composed of 5 identical,
21,500-molecular weight subunits. CRP mediates activities
associated with preimmune nonspecific host resistance. CRP
shows the strongest association with cardiovascular events.
It is detectable on the surface of about 4% of normal
peripheral blood lymphocytes. Acute phase reactant CRP is
produced in the liver.
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Catalog Number
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IW-PA1028 |
Quantity
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9 ml |
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Host
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Rabbit
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Clone
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Polyclonal
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Isotype
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IgG
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Immunogen
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A synthetic peptide
corresponding to a sequence at the N-terminal of human CRP,
identical to the related rat and mouse sequence.
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Purity
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Immunogen affinity
purified
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Conjugate
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Unconjugated
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Species Reactivity
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Human, mouse, rat.
Not tested
in other species. |
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Positive Control
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Liver, cardiac muscle
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Cellular Localization
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Cytoplasmic
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Form
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Ready to use
solution. No further dilution needed. Serum blocking step
should be omitted.
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Storage
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Store at 2-8
°C.
Do not freeze.
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Applications
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IHC-P: Heat induced
epitope retrieval enhance stain on formalin fixed paraffin
sections.
IHC-Fr: Not tested.
ICC: Not tested.
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Limitations
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This product is intended
for Research Use Only. Interpretation of the test
results is solely the responsibility of the user.
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Precautions
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Users should follow
general laboratory precautions when handling this product.
Wear personal protective equipment to avoid contact with
skin and eyes.
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References
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1.
Kilpatrick, J. M.; Volanakis, J.
E. : Molecular
genetics, structure, and function of C-reactive protein.
Immun. Res. 10: 43-53, 1991.
2.Kuta, A.
E.; Baum, L. L. :
C-reactive protein is produced by a small number of normal
human peripheral blood lymphocytes. J. Exp. Med.
164: 321-326, 1986.
3.Oliveira,
E. B.; Gotshlich, E. C.; Liu, T. :
Primary structure of
human C-reactive protein. J. Biol. Chem. 254:
489-502, 1979.
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Images
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Immunohistochemical analysis of formalin fixed paraffin-embedded rat cardiac muscle tissue using CRP antibody
Immunohistochemical staining of formalin fixed paraffin-embedded human liver using CRP antibody showing cytoplasmic staining pattern of hepatocytes.
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