Catalog Number | Size | Price | Availability |
IW-PA1032 | 9 ml | $258 | Yes |
Description
|
FGF2 has been implicated in a multitude of physiologic and
pathologic processes, including limb development,
angiogenesis, wound healing, and tumor growth. FGF2 belongs
to the fibroblast growth factor (FGF) family. Fibroblast
growth factors (FGFs) exhibit widespread mitogenic and
neurotrophic activities. Nine members of the family are
currently known, and FGF-1 and FGF-2 are present in
relatively high levels in CNS. FGF-2 is expressed by at low
levels in many tissues and cell types and reaches high
concentrations in brain and pituitary. |
Catalog Number
|
IW-PA1032 |
Quantity
|
9 ml |
Host |
Rabbit |
Clone |
Polyclonal |
Isotype |
IgG |
Immunogen |
A peptide mapping near the N-terminal of human FGF2,
identical to the related rat and mouse sequence. |
Purity |
Immunogen affinity purified |
Conjugate |
Unconjugated |
Species Reactivity |
Human,
mouse, rat.
Not tested in other species. |
Positive Control |
Human mammary cancer |
Cellular Localization |
Cytoplasmic |
Form |
Ready to use solution. No further dilution needed. Serum blocking step should be omitted. |
Storage |
Store at 2-8
°C.
Do not freeze. |
Applications |
IHC-P: Heat induced epitope retrieval is required on
formalin fixed paraffin sections.
IHC-Fr: Not tested.
ICC: Not tested. |
Limitations |
This product is intended for Research Use Only.
Interpretation of the test results is solely the
responsibility of the user. |
Precautions |
Users should follow general laboratory precautions when
handling this product. Wear personal protective equipment to
avoid contact with skin and eyes. |
References |
1.
Doniach, T. :
Basic FGF as an
inducer of anteroposterior neural pattern. Cell
83: 1067-1070, 1995
2. Eckenstein, F. P. :
Fibroblast growth
factors in the nervous system. J. Neurobiol.
25: 1467-1480, 1994. |
Images |
Immunohistochemical analysis of formalin fixed paraffin-embedded
human mammary cancer tissue using FGF2 antibody.
Staining FGF2 in cytoplasm. DAB chromogenic reaction |
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