Catalog Number | Size | Price | Availability |
IW-PA1033 | 9 ml | $258 | Yes |
Description
|
Fibroblast growth factor 4 (FGF4) also knows as Heparin
Secretary Transforming (HSTF1). HST1, for which the
designation HSTF1 was proposed for human gene nomenclature,
is a heparin-binding growth factor with significant homology
to human fibroblast growth factors and the mouse Int-2
protein. By in situ hybridization,
Adelaide et al. (1988) mapped the HST gene to
chromosome 11q13. The HST1 protein is a heparin-binding
growth factor with significant homology with human
fibroblast growth factors and the mouse Int-2 protein. |
Catalog Number
|
IW-PA1033 |
Quantity
|
9 ml |
Host |
Rabbit |
Clone |
Polyclonal |
Isotype |
IgG |
Immunogen |
A synthetic peptide corresponding to a sequence at the
C-terminal of the human FGF4, identical to the related mouse
sequence. |
Purity |
Immunogen affinity purified |
Conjugate |
Unconjugated |
Species Reactivity |
Human,
mouse, rat.
Not tested in other species. |
Positive Control |
Human lung cancer |
Cellular Localization |
Cytoplasmic |
Form |
Ready to use solution. No further dilution needed. Serum blocking step should be omitted. |
Storage |
Store at 2-8
°C. Do not freeze. |
Applications |
IHC-P: Heat induced epitope retrieval is required on
formalin fixed paraffin sections.
IHC-Fr: Not tested.
ICC: Not tested. |
Limitations |
This product is intended for Research Use Only.
Interpretation of the test results is solely the
responsibility of the user. |
Precautions |
Users should follow general laboratory precautions when
handling this product. Wear personal protective equipment to
avoid contact with skin and eyes. |
References |
1. Huebner, K.; Ferrari, A. C.; Delli Bovi, P.; Croce, C.
M.; Basilico, C. :
The FGF-related oncogene, K-FGF, maps to human chromosome
region 11q13, possibly near int-2. Oncogene Res.
3: 263-270, 1988.
2. Adelaide, J.; Mattei, M.-G.; Marics, I.; Raybaud, F.;
Planche, J.; De Lapeyriere, O.; Birnbaum, D. :
Chromosomal localization of the hst oncogene and its co-amplification
with the int.2 oncogene in a human melanoma.
Oncogene 2: 413-416, 1988.
3. Yoshida, T.; Tsutsumi, M.; Sakamoto, H.; Miyagawa, K.;
Teshima, S.; Sugimura, T.; Terada, M. :
Expression of the HST1 oncogene in human germ cell tumors.
Biochem. Biophys. Res. Commun. 155: 1324-1329, 1988. |
Images |
Immunohistochemical analysis of formalin fixed paraffin-embedded human lung cancer section using FGF4 antibody showing cytoplasmic staining.
|
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