GLUT1 IHC Antibody


Ready To Use


Catalog Number Size Price Availability
IW-PA1120 9 ml $258 Yes


GLUT1,also known as SLC2A1, is a major glucose transporter in the mammalian blood-brain barrier whose gene is mapped to 1p35-p31.3 and contains 10 exons. It is present at high levels in primate erythrocytes and brain endothelial cells. Not only can transport dehydroascorbic acid (the oxidized form of vitamin C) into the brain1, GLUT1 is also likely to contribute to HTLV-associated disorders through interacting with HTLV envelope glycoproteins2. Functionally,  GLUT1 deficiency causes a decrease in embryonic glucose uptake and apoptosis, which may be involved in diabetic embryopathy3, by contrast, an increased expression of GLUT1 in some malignant tumors may suggest a role for glucose-derivative tracers to detect in vivo thyroid cancer metastases by positron-emission tomography scanning.


Catalog Number





9 ml















A peptide mapping very near  the N-terminal end  of  GAD67 of human origin, identical to the related mouse sequence.




Immunogen affinity purified






Species Reactivity


Human, mouse, rat. Not tested in other species.

Positive Control


Cardiac muscle, human adenocarcinoma endometrium.


Cellular Localization






Ready to use solution. No further dilution needed. Serum blocking step should be omitted.




Store at 2-8 °C. Do not freeze.




IHC-P: Heat induced epitope retrieval is required on formalin fixed paraffin sections.

IHC-Fr: Not tested.

ICC: Suitable.




This product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.




Users should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.




1.Agus, D. B.; Gambhir, S. S.; Pardridge, W. M.; Spielholz, C.; Baselga, J.; Vera, J. C.; Golde, D. W. : Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters. J. Clin. Invest. 100: 2842-2848, 1997.

2.Manel, N.; Kim, F. J.; Kinet, S.; Taylor, N.; Sitbon, M.; Battini, J.-L. : The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell 115: 449-459, 2003.

3.Heilig, C. W.; Saunders, T.; Brosius, F. C., III; Moley, K.; Heilig, K.; Baggs, R.; Guo, L.; Conner, D. : Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy. Proc. Nat. Acad. Sci. 100: 15613-15618, 2003.

4.Lazar, V.; Bidart, J.-M.; Caillou, B.; Mahe, C.; Lacroix, L.; Filetti, S.; Schlumberger, M. : Expression of the Na(+)/I(-) symporter gene in human thyroid tumors: a comparison study with other thyroid-specific genes. J. Clin. Endocr. Metab. 84: 3228-3234, 1999.




Immunohistochemical analysis of formalin fixed paraffin-embedded rat cardiac muscle using Glut1 antibody


Immunohistochemical analysis of formalin fixed paraffin-embedded human adenocarcinoma endometrium using Glut1 antibody showing cytoplasmic staining pattern.


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