Catalog Number | Size | Price | Availability |
IW-MA1047 | 9 ml | $258 | Yes |
Description
|
Glucagon is a member of a multigene family that includes
secretin. Glucagon is a 29-amino acid pancreatic hormone
that counteracts the glucose-lowering action of insulin by
stimulating glycogenolysis and gluconeogenesis. the human
glucagon gene is approximately 9.4 kb long and contains 6
exons and 5 introns, and assigned to 2q36-2q37.
|
Catalog Number
|
IW-MA1047 |
Quantity
|
9 ml |
Host
|
Mouse
|
Clone
|
IMD-7
|
Isotype
|
Mouse IgG1
|
Immunogen
|
Polymerized porcine glucagon. |
Purity
|
Purified by the goat anti-mouse IgG affinity chromatography. |
Conjugate
|
Unconjugated
|
Species Reactivity
|
Human,
rat.
Not
tested in other species. |
Positive Control
|
Pancreas.
|
Cellular Localization
|
Cytoplasmic
|
Form
|
Ready to use solution. No further dilution needed. Serum blocking
step should be omitted.
|
Storage
|
Store at 2-8
°C. Do not freeze.
|
Applications
|
IHC-P: Formalin fixed paraffin embedded tissue sections.
IHC-Fr: Not tested.
ICC: Not tested.
|
Limitations
|
This product is intended for Research Use Only.
Interpretation of the test results is solely the
responsibility of the user.
|
Precautions
|
Users should follow general laboratory precautions when
handling this product. Wear personal protective equipment to
avoid contact with skin and eyes.
|
References
|
1. Schroeder, W. T.; Lopez, L. C.; Harper, M. E.; Saunders, G. F.
: Localization of
the human glucagon gene (GCG) to chromosome segment 2q36-37.
Cytogenet.
Cell Genet. 38: 76-79, 1984.
2. White, J. W.; Saunders, G. F. :
Structure of the
human glucagon gene.
Nucleic Acids Res.
14: 4719-4730, 1986.
|
Images
|
Immunohistochemistry staining of formalin fixed paraffin-embedded rat pancreas section using Glucagon antibody showing cytoplasmic staining.
|
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