Catalog Number | Size | Price | Availability |
IW-PA1043 | 9 ml | $258 | Yes |
Description
|
The Hsp40 (heat shock
protein with molecular size of approximately 40 kDa) is one
of the mammalian homologues of bacterial DnaJ heat shock
protein.
Ohtsuka (1993) isolated a cDNA encoding a 40-kD
heat-shock protein designated HSPF1. The deduced 340-amino
acid HSPF1 protein is 34% identical to E. coli DnaJ and 34%
and 36% identical to HSJ1 and HSJ2, respectively. HSPF1 gene
spans over 7 kb and contains 3 exons and 2 introns. HSPF1
gene is mapped to chromosome 19p13.2.
|
Catalog Number
|
IW-PA1043 |
Quantity
|
9 ml |
Host
|
Rabbit
|
Clone
|
Polyclonal
|
Isotype
|
IgG
|
Immunogen
|
A peptide mapping at the
C-terminal end of human HSP40, different from the related
rat and mouse sequence by two amino acids.
|
Purity
|
Immunogen affinity
purified
|
Conjugate
|
Unconjugated
|
Species Reactivity
|
Human, mouse, rat.
Not tested in other species. |
Positive Control
|
Human mammary cancer
|
Cellular Localization
|
Cytoplasmic
|
Form
|
Ready to use
solution. No further dilution needed. Serum blocking step
should be omitted.
|
Storage
|
Store at 2-8
°C.
Do not freeze.
|
Applications
|
IHC-P: Heat induced
epitope retrieval is required on formalin fixed paraffin
sections.
IHC-Fr: Not tested.
ICC: Not tested.
|
Limitations
|
This product is intended
for Research Use Only. Interpretation of the test
results is solely the responsibility of the user.
|
Precautions
|
Users should follow
general laboratory precautions when handling this product.
Wear personal protective equipment to avoid contact with
skin and eyes.
|
References
|
Hata, M.;
Okumura, K.; Seto, M.; Ohtsuka, K. :
Genomic cloning of a
human heat shock protein 40 (Hsp40) gene (HSPF1) and its
chromosomal localization to 19p13.2. Genomics
38: 446-449, 1996.
|
Images
|
Immunohistochemical
analysis of formalin fixed paraffin-embedded human mammary cancer
using HSP40 antibody
|
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