Catalog Number | Size | Price | Availability |
IW-MA1043 | 9 ml | $258 | Yes |
Description |
The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Mucin gastric 6 (MUC6) is a large glycoprotein thought to play a major role in protecting the gastrointestinal tract from acid, proteases, pathogenic microorganisms and mechanical trauma. Expression of the gene was highest in the stomach and gallbladder, with weaker expression in the terminal ileum and right colon. Mucin glycoproteins play a key role in the normal function of the epithelium lining the gastrointestinal tract.
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Catalog Number
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IW-MA1043
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Quantity
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9 ml
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Host |
Mouse
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Clone |
GM-8A12
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Isotype |
Mouse IgG1
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Immunogen |
Mucin from human ovarian cystfluid.
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Purity |
Purified by the goat anti-mouse IgG affinity chromatography.
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Conjugate |
Unconjugated
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Species Reactivity |
Human. Not tested in other species.
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Positive Control |
Stomach, normal gastric mucosa
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Cellular
Localization |
Cytoplasmic
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Form |
Ready to use solution. No further dilution needed. Serum blocking step should be omitted.
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Storage |
Store at 2-8 °C. Do not freeze.
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Applications |
IHC-P: Heat
induced epitope retrieval is required on formalin fixed
paraffin embedded sections.
IHC-Fr: Not
tested. ICC: Suitable.
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Limitations |
This product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.
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Precautions |
Users should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.
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References |
1. Reid, C. J.; Harris, A. : Developmental expression of
mucin genes in the human gastrointestinal system. Gut 42:
220-226, 1998. |
Images |
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