Catalog Number | Size | Price | Availability |
IW-PA1061 | 9 ml | $258 | Yes |
Description
|
NSE (neuron specific enolase) also knows as Enolase
2(ENO2), is found in elevated concentrations in plasma in
certain neoplasias. The enolases catalyze the
interconversion of 2-phosphoglycerate to phosphoenolpyruvate
in the glycolytic pathway. ENO2 gene contains 12 exons
distributed over 9,213 nucleotides.
Human neurone-specific
enolase is mapped to chromosome 12p13. |
Catalog Number
|
IW-PA1061 |
Quantity
|
9 ml |
Host |
Rabbit |
Clone |
Polyclonal |
Isotype |
IgG |
Immunogen |
A peptide mapping at the C-terminus of NSE of human origin,
identical to the related mouse and rat sequence. |
Purity |
Immunogen affinity purified |
Conjugate |
Unconjugated |
Species Reactivity |
Human, mouse, rat.
Not tested in other species. |
Positive Control |
Brain |
Cellular Localization |
Cytoplasmic |
Form |
Ready to use solution. No further dilution needed. Serum blocking step should be omitted. |
Storage |
Store at 2-8
°C. Do not freeze. |
Applications |
IHC-P: Heat induced epitope retrieval or proteinase K pretreatment is required on formalin fixed paraffin embedded sections. IHC-Tek Epitope Retrieval Solution (Cat# IW-1100) or IHC-Tek Proteinase K Solution (IW-1101) is recommended.
IHC-Fr: Not tested.
ICC: Suitable. |
Limitations |
This product is intended for Research Use Only.
Interpretation of the test results is solely the
responsibility of the user. |
Precautions |
Users should follow general laboratory precautions when
handling this product. Wear personal protective equipment to
avoid contact with skin and eyes. |
References |
1. Craig, S. P.; Day, I. N. M.;
Thompson, R. J.; Craig, I. W. :
Localization of
human neurone-specific enolase to chromosome 12p13.
(Abstract)
Cytogenet. Cell Genet. 51: 980 only, 1989.
2. Craig, S. P.; Day, I. N. M.;
Thompson, R. J.; Craig, I. W. :
Localisation of
neurone-specific enolase (ENO2) to 12p13.
Cytogenet. Cell Genet. 54: 71-73, 1990.
3. Mattei, J. F.; Baeteman, M.
A.; Mattei, M. G.; Ardissonne, J. P.; Giraud, F. :
Regional assignments of CS and ENO2 on chromosome 12. (Abstract)
Cytogenet. Cell
Genet. 32: 297 only, 1982.
|
Images |
Immunohistochemical analysis of formalin fixed paraffin-embedded
rat brain using
NSE antibody
IHC staining of formalin fixed paraffin embedded human pancreas using NSE antibody showing cytoplasmic staining pattern of islet cells.
IHC staining of formalin fixed paraffin embedded human testis using NSE antibody showing cytoplasmic staining pattern of leydig cells. |
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