Catalog Number | Size | Price | Availability |
IW-MA1100 | 9 ml | $258 | Yes |
Description |
Tyrosine hydroxylase is involved in the conversion of
phenylalanine to dopamine. As the rate-limiting enzyme in
the synthesis of catecholamines, tyrosine hydroxylase has a
key role in the physiology of adrenergic neurons. Human TH gene contains 13
primary exons and spans approximately 8 kb. TH is in the 11p15.5
region.
|
Catalog Number
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IW-MA1100
|
Quantity
|
9 ml
|
Host |
Mouse
|
Clone |
TH-100
|
Isotype |
Mouse IgG1
|
Immunogen |
Rat tyrosine hydroxylase (TH)
|
Purity |
Purified by the goat anti-mouse IgG affinity chromatography.
|
Conjugate |
Unconjugated
|
Species Reactivity |
Human, rat. Not tested in other species.
|
Positive Control |
Brain (striatum, substantia nigra)
|
Cellular Localization |
Cytoplasmic of dopamine neurons.
|
Form |
Ready to use solution. No further dilution needed. Serum blocking step should be omitted.
|
Storage |
Store at 2-8 °C. Do not freeze.
|
Applications |
IHC-P: Heat induced epitope retrieval is
required on formalin fixed paraffin embedded sections. IHC-Fr: Formalin or acetone fixed frozen
sections. ICC: Not tested.
|
Limitations |
This product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.
|
Precautions |
Users should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.
|
References |
1. Brilliant,
M. H.; Niemann, M. M.; Eicher, E. M. :
urine tyrosine
hydroxylase maps to the distal end of chromosome 7 within a
region conserved in mouse and man. J. Neurogenet.
4: 259-266, 1987. 2. Craig, S. P.;
Buckle, V. J.; Craig, I. W.; Lamouroux, A.; Mallet, J. :
Localization of the
human tyrosine hydroxylase gene to chromosome 11p15.
(Abstract) Cytogenet. Cell
Genet. 40: 610 only,
1985. 3. Craig, S. P.; Buckle, V. J.; Lamouroux, A.; Mallet, J.; Craig, I. : Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways. Cytogenet. Cell Genet. 42: 29-32, 1986. |
Images |
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