 |
|
alpha-SMA IHC Antibody
Ready To Use
| Catalog Number | Size | Price | Availability |
| IW-MA1106 | 9 ml | $258 | Yes |
Description
|
Ueyama et al. (1990) assigned the ACTSA gene to
chromosome 10 by Southern blot analysis of DNAs from 18
rodent-human somatic cell hybrids. Regional mapping by in
situ hybridization localized the gene to 10q22-q24.Assignment
of the vascular smooth muscle actin gene ACTSA to human
chromosome. Smooth muscle alpha-actin gene requires
two E-boxes for proper expression in vivo and is a target of
class I basic helix-loop-helix proteins. |
Catalog Number
|
IW-MA1106 |
Quantity
|
9 ml |
|
Host
|
Mouse
|
|
Clone
|
1A4
|
|
Isotype
|
Mouse IgG2a
|
|
Immunogen
|
N-terminal synthetic decapeptide of α-smooth muscle actin. |
|
Purity
|
Purified by the goat anti-mouse IgG affinity chromatography. |
|
Conjugate
|
Unconjugated
|
|
Species Reactivity
|
Human, mouse, rat.
Not tested in other species. |
|
Positive Control
|
Smooth muscle, colon, skin, human tonsil. |
|
Cellular Localization
|
Membrane/cytoplasmic
|
|
Form
|
Ready to use solution. No further dilution needed. Serum
blocking step should be omitted.
|
|
Storage
|
Store at 2-8
°C.
Do not freeze.
|
|
Applications
|
IHC-P: Pretreatment is NOT required on formalin fixed
paraffin sections.
IHC-Fr: Not tested.
ICC: Not tested.
|
|
Limitations
|
This product is intended for Research Use Only.
Interpretation of the test results is solely the
responsibility of the user.
|
|
Precautions
|
Users should follow general laboratory precautions when
handling this product. Wear personal protective equipment to
avoid contact with skin and eyes.
|
|
References
|
1. Kumar, M. S.; Hendrix, J. A.; Johnson, A. D.; Owens, G.
K. : Smooth muscle
alpha-actin gene requires two E-boxes for proper expression
in vivo and is a target of class I basic helix-loop-helix
proteins.
Circ. Res. 92: 840-847, 2003.
2. Ueyama, H.; Bruns, G.; Kanda,
N. : Assignment of
the vascular smooth muscle actin gene ACTSA to human
chromosome 10.
Jpn. J. Hum.
Genet. 35: 145-150, 1990.
|
|
Images
|
|
Related Products