Catalog Number | Size | Price | Availability |
IW-MA1107 | 9 ml | $258 | Yes |
Description |
alpha-tubulin (b-alpha-1) mRNA is expressed only in brain with a molecular weight of about 55,000. The 3-prime UTR of b-alpha-1 is more than 80% homologous to the UTR of the rat brain alpha-tubulin gene, IL-alpha-T1. B-alpha-1 encodes a predicted 451-amino acid protein that is 100% identical to the rat homolog and differs by only 2 and 3 amino acids from the pig and chicken homologs, respectively.
|
Catalog Number
|
IW-MA1107 |
Quantity
|
9 ml |
Host |
Mouse |
Clone |
Tub-1 |
Isotype |
Mouse IgG1 |
Immunogen |
Microtubules from
chicken embryo brain. |
Purity |
Purified by the goat anti-mouse IgG
affinity chromatography. |
Conjugate |
Unconjugated |
Species Reactivity |
Human, rat.
Not tested in
other species. |
Positive Control |
Brain |
Cellular Localization |
Cytoplasmic |
Form |
Ready to use solution. No further
dilution needed. Serum blocking step should be omitted. |
Storage |
Store at 2-8
°C. Do not freeze. |
Applications |
IHC-P: Heat induced epitope retrieval is
required on formalin fixed paraffin sections. IHC-Fr: Not tested. ICC: Not tested. |
Limitations |
This product is intended for Research
Use Only. Interpretation of the test results is solely
the responsibility of the user. |
Precautions |
Users should follow general laboratory
precautions when handling this product. Wear personal
protective equipment to avoid contact with skin and eyes. |
References |
1. Cowan, N.
J.; Dobner, P. R.; Fuchs, E. V.; Cleveland, D. W. :
Expression of human
alpha-tubulin genes: interspecies conservation of 3-prime
untranslated regions.
Molec. Cell. Biol.
3: 1738-1745, 1983. 2. Hall, J.
L.; Cowan, N. J. :
Structural features and restricted expression of a human
alpha-tubulin gene.
Nucleic Acids Res.
13: 207-223, 1985. |
Images |
Immunohistochemistry staining of formalin fixed paraffin embedded human mammary cancer using alpha-Tubulin antibody showing cytoplasmic staining. |
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