Description

Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues.

Catalog Number

IW-MA1081

Quantity

9 ml

Host

Mouse

Clone

IML-91

Isotype

Mouse IgG2a/IgG1

Immunogen

Mixture of several monoclonal cytokeratin clones.

Purity

Purified by the goat anti-mouse IgG affinity chromatography.

Conjugate

Unconjugated

Species Reactivity

Human, rat. Not tested in other species.

Positive Control

Skin, lung, pancreas, kidney.

Cellular Localization

Cytoplasmic

Form

Ready to use solution. No further dilution needed. Serum blocking step should be omitted.

Storage

Store at 2-8 °C. Do not freeze.

Applications

IHC-P: Heat induced epitope retrieval is required on formalin fixed paraffin sections.

IHC-Fr: Formalin or acetone fixed frozen tissues.

ICC: Not tested.

Limitations

This product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.

Precautions

Users should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.

References

1. Rastaldi MP et al. Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J 20:976-8 (2006).

2. Wen J et al. Use of superparamagnetic microbeads in tracking subretinal injections. Mol Vis 11:256-62 (2005).

Images

Immunohistochemical analysis of formalin fixed paraffin embedded human placenta using pan-Cytokeratin antibody.