ABC of Safety in the Biological Sciences
EOSIN Y (Colour Index No. 45380) (C20H6O5Br4Na2)
SYNONYMS
Eosin, eosin C, eosin WG, bromo acid, bromo acid J, bromo acid
TS, bromo acid XL, bromo acid XX, bromofluoroescein, bronze
bromo YS, acid red 87, eosine yellowish, tetrabromofluorescein
S, bromoeosine, disodium eosin, eosine sodium salt, sodium
eosine.
CHARACTERISTICS
Red crystals or brownishred powder. Xanthine group of dyes.
INCOMPATIBILITY
Heating produces highly toxic fumes of bromine.
HEALTH HAZARD DATA
There have been indefinite reports that this substance is an
animal carcinogen. It is a skin, eye and mucous membrane
irritant. Acute exposure to the skin may cause irritation,
cheilitis and stomatitis. Prolonged skin contact may cause
dermatitis. Acute exposure to the eyes will cause redness,
localised pain and irritation. There is no data available about
the effects of inhalation or ingestion in humans.
HANDLING and GENERAL PRECAUTIONS
Use a fume hood.
Avoid skin and eye contact.
Keep away from heat.
Wash hands thoroughly after handling.
There have been indefinite reports that eosin Y may be an animal
carcinogen. Until it is positively known that eosin Y is not an
animal carcinogen this dye should be handled as though it is a
carcinogen. Use a fume hood to keep the level of exposure to a
minimum. Wear protective clothing. A long sleeved laboratory
coat or gown, rubber gloves, safety goggles and a face mask as a
minimum standard.
TREATMENTS
Skin immediately wash the affected area with soap or mild
detergent and large amounts of water until all evidence of the
chemical has been removed (approximately 15 minutes). If
irritation persists or dermatitis develops seek medical
attention.
Eyes immediately wash the affected eye with large amounts of
water until all evidence of the dye has been removed
(approximately 15 minutes). If irritation or pain persist seek
immediate medical attention.
Inhalation remove from the area of exposure to fresh air. Keep
warm and allow to rest. If irritation develops and persists seek
medical attention.
Ingestion wash out the mouth thoroughly with water and give
two to four glasses of water to drink. Induce vomiting by
touching a finger to the back of the throat. If discomfort
persists seek medical advice. Never give anything by mouth to a
person that is not conscious.
STORAGE
Store in a cool, dry atmosphere away from heat.
DISPOSAL
WEAR:
Butyl rubber gloves, laboratory coat, self contained breathing
apparatus and protective shoes.
SPILLS:
On skin and clothing: wash skin with a strong soap solution
immediately. Rinse well. Contaminated clothing should be removed
and cleaned at once or destroyed by burning.
Small spills: absorb liquid on paper towels or vermiculite;
sweep solid spills on to paper. Put on an iron pan in a fume
hood and allow to evaporate. Burn the paper or vermiculite in
the absence of other inflammables. Wash the site thoroughly with
a strong soap solution.
Large spills: absorb or mix with vermiculite, sodium bicarbonate
or sand. Package this in a paper carton and burn in an open pit.
Use wood scraps and crumpled paper to augment burning. Wash the
site thoroughly with a strong soap solution.
PACKAGE LOTS: Either
1 Pour os sift on to sodium bicarbonate or a sand, soda ash
mixture (90/10). Mix and package in heavy paper cartons with
plenty of paper packing to serve as fuel. Burn in an
incinerator.
OR
2 Mix with a flammable solvent and spray into a firebox of an
incinerator equipped with an afterburner and scrubber.
NOTE:
Destruction by chemical decomposition is recommended for dinitro,
trinitro and other compounds with explosive potential. Add the
material, slowly, while stirring, to 30 times its weight of a
solution prepared by dissolving 1 part sodium sulphide in 6
parts water. For unstable acidic materials (eg. picric acid)
dissolve in 25 times its weight in a solution from 1 part sodium
hydroxide and 21 parts sodium sulphide in 200 parts water. Some
hydrogen sulphide and ammonia is evolved.
ENVIRONMENT:
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