ABC of Safety in the Biological Sciences
N-METHYLANILINE C6H5-NH-CH3
SYNONYMS
Anilinomethane, methylphemylamine, n-methylaminobenzene, n-methylphenylamine,
n-methylbenzeneamine, methylaniline-n, monomethylaniline,
methylaniline.
GENERAL PRECAUTIONS
Very toxic substance.
Keep away from eyes and skin.
Avoid inhalation and ingestion.
Keep away from heat or naked flames.
Wear protective clothing.
Keep away from strong oxidising agents.
CHARACTERISTICS
Colourless to light yellow, oily liquid (browns on exposure to
air).
HEALTH HAZARD DATA
Combustible substance. TLV 0.5ppm (2mg/m3). Odour
threshold approximately 7mg/m3. Odour threshold is
above the TLV. Very toxic substance. Eye irritant and can cause
corneal damage if not removed quickly. High concentrations of
vapour can also damage the eye. Readily absorbed through the
skin, can be absorbed through the skin in doses sufficient to
cause narcosis. Inhalation, ingestion and skin absorption
produce the same symptoms. Symptoms include headache, shortness
of breath, weakness, nausea, confusion, stupor, lowering of
blood pressure and cyanosis. Prolonged exposure can result in
convulsion, coma and death from methemoglobinaemia. Chronic
exposure may cause incoordination, irritability, liver and
kidney damage, bone marrow damage, weight loss, anaemia and
weakness.
TREATMENTS
Skin - Immediately wash the affected area with soap or mild
detergent and large amounts of water until all evidence of the
chemical has been removed (approximately 15 minutes). If signs
of toxicity or burning develops seek immediate medical
attention. Remove contaminated clothing and shoes and
decontaminate before re-use.
Eyes - Immediately wash the affected eye with large amounts of
water until all evidence of the chemical has been removed
(approximately 15 minutes). If irritation or burning pain
persists seek immediate medical attention.
Inhalation - Remove from the area of exposure to fresh air. Keep
warm and allow to rest. Give artificial respiration if
necessary. Seek immediate medical attention.
Ingestion - Never give anything by mouth if the victim is losing
consciousness, is unconscious or convulsing. Rinse the mouth
thoroughly with water. Induce vomiting by giving Ipecac syrup.
Seek immediate medical attention.
INCOMPATIBILITY
Avoid strong oxidising agents.
STORAGE
Store in a cool, dry, well ventilated atmosphere away from heat
and incompatible substances. Keep tightly closed.
HANDLING
Wear protective clothing. A long sleeved laboratory coat or gown
with elasticised wrist bands, rubber gloves and safety goggles
as a minimum standard. If a fume hood is not available wear a
suitable respirator.
DISPOSAL
For small spills absorb on absorbant paper. Place in a fume hood
and allow to evaporate then burn the paper. For large quantity
disposal burn in a high temperature incinerator equipped with an
afterburner and scrubber.
ENVIRONMENT
No data available.
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