ABC of Safety in the Biological Sciences
PHLOXINE B (Colour Index No. 45410) (C20H2O5Br4Cl4Na2)
SYNONYMS
Phloxine TA, N, BF, RB, TB, BB, cyanosine, eosin 10B, magdala
red, acid red 92, eosine blue.
GENERAL PRECAUTIONS
Avoid eye contact.
Avoid inhalation or ingestion of the powder.
Keep away from heat.
Wash hands thoroughly after handling.
CHARACTERISTICS
Reddishbrown powder. Xanthene group of dyes.
HEALTH HAZARD DATA
Phloxine is highly toxic via the intravenous route. Other data
has not been quantified although because of its chemical
structure it is assumed to be an eye and skin irritant. It
causes foetal death in animals.
TREATMENTS
Skin remove contaminated clothing then wash the affected area
with soap or mild detergent and large amounts of water until all
evidence of the dye has been removed (approximately 15 minutes).
If irritation persists seek medical advice. Wash contaminated
clothing before reuse.
Eyes immediately wash the affected eye with large amounts of
water until all evidence of the dye has been removed
(approximately 15 minutes). If irritation persists seek
immediate medical attention.
Inhalation remove from the area of exposure to fresh air. If
breathing has ceased apply artificial respiration. Give oxygen
if required. Keep warm and allow to rest. Seek immediate medical
attention.
Ingestion wash out the mouth thoroughly with water. If the
victim is conscious, induce vomiting by touching a finger to the
back of the throat. Seek immediate medical attention.
INCOMPATIBILITY
Heating produces toxic fumes of chlorine, bromine and sodium
oxide.
STORAGE
Store in a cool, dry atmosphere away from heat.
HANDLING
Use a fume hood to keep the level of exposure to a minimum. Wear
protective clothing. A long sleeved laboratory coat or gown,
rubber gloves, safety goggles and a face mask as a minimum
standard.
DISPOSAL
WEAR:
Rubber gloves, self contained breathing apparatus and laboratory
coat.
SPILLS:
Eliminate all sources of ignition. Absorb on paper towels or
with vermiculite. Place on an iron, glass or plastic dish in a
fume hood. Allow to evaporate. burn the paper or vermiculite.
Wash the site with a soapy solution.
PACKAGE LOTS: Either
1 Pour on to vermiculite, sodium bicarbonate or sand-soda ash
mixture (90/10). If a fluoride is present, add slaked lime to
the mixture. Mix and shovel into paper boxes. place in an open
incinerator, cover with scrap wood and paper then ignite with a
torch or fuse. Stay on the upwind side.
OR
2 Dissolve in a flammable solvent. Spray into a fire box of an
incinerator equipped with an afterburner and scrubber.
ENVIRONMENT:
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