ABC of Safety in the Biological Sciences




A mutagen is an agent that alters the genetic material of a living cell.27 (Mutagens are not to be confused with carcinogens). There is no comprehensive list of proven mutagens therefore all substances should be considered as potentially dangerous. All available information on any new substance should be obtained before its introduction to the laboratory (also see Toxic Chemicals).

Some known mutagens commonly used in histopathology are:
ammonium bromide
auramine O
carbon tetrachloride
crystal violet
ethylene glycol
indigo carmine
methyl orange
methylene blue
orange G
sodium chloride (in excess amounts)
Sudan III
Sudan IV
toluidine blue.


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