Histopathology Artifacts Quiz



This Micrograph shows perivascular separation of dense nervous tissue at the junction of the adventitia and glial membrane. It is due to poor fixation and can largely be avoided by perfusion fixation and gentle, prolonged processing using chloroform as a clearing agent. A similar effect can frequently be seen around large neurones. Give yourself one mark if your answer is perivascular shrinkage.

© Roy C. Ellis 2004