Histopathology Artifacts Quiz



The skin contains black deposits of very finely granular material in the reticular dermis, where it is located free in the tissue rather than in the cytoplasm of phagocytic cells. There appears to be no tissue reaction to the presence of the deposits. This deposit is tattoo pigment, one of a range of different coloured, insoluble pigments used in producing decorative colours on the skin and sometimes not mentioned in documentation accompanying the specimen to the laboratory. These deposits are generally unreactive to histochemical tests and are not birefringent under polarised light. Answer tattoo pigment.

© Roy C. Ellis 2004